ONE OF MEREDITH'S OLDEST FRIENDS BECOMES AN INTERN AT SEATTLE GRACE, CAUSING TURMOIL AT THE HOSPITAL AND IN MER'S PERSONAL LIFE, ON ABC'S "GREY'S ANATOMY"

Guest Starring Kevin McKidd ("Rome") as Owen Hunt and Melissa George ("Alias," "In Treatment") as Sadie

Also Guest Starring Academy Award �-nominated Actress Mary McDonnell ("Passion Fish," "Battlestar Gallactica")

"These Ties That Bind" � One of Meredith's oldest friends, Sadie, becomes an intern at Seattle Grace, but Mer's friends are less-than-welcoming to her; Lexie leads her fellow interns in secretive, unorthodox surgical training sessions; and a new surgeon, Virginia Dixon, brings rules and order to the OR, on "Grey's Anatomy," THURSDAY, NOVEMBER 13 (9:00-10:01 p.m., ET) on the ABC Television Network

"Grey's Anatomy" stars Ellen Pompeo as Meredith Grey, Patrick Dempsey as Derek Shepherd, Sandra Oh as Cristina Yang, Katherine Heigl as Isobel "Izzie" Stevens, Justin Chambers as Alex Karev, T.R. Knight as George O'Malley, Chandra Wilson as Miranda Bailey, James Pickens, Jr. as Richard Webber, Sara Ramirez as Callie Torres, Eric Dane as Mark Sloan, Chyler Leigh as Lexie Grey and Brooke Smith as Erica Hahn.

Guest stars TBD.

"These Ties That Bind" was written by Stacey McKee and directed by Eric Stoltz.

"Grey's Anatomy" is broadcast in 720 Progressive (720P), ABC's selected HDTV format, with 5.1-channel surround sound and Spanish audio via SAP. A TV parental guideline will be posted closer to airdate.

This episode of "Grey's Anatomy" will be available on ABC.com the day after airing on the network for users to watch online.