DR. HOUSE'S DIAGNOSIS OF A MARRIED WOMAN WITH A RARE SLEEP DISORDER FORCES HER AND HER HUSBAND TO EXAMINE THEIR MARRIAGE AND QUESTION THEIR TRUST FOR EACH OTHER ON "HOUSE" TUESDAY, DECEMBER 28, ON FOX

Dominic Purcell Guest-Stars

When young wife Elyse falls ill with a rare disease she can't possibly have, Dr. Cameron is very interested in the case � so much so that her interest convinces House to take the case, and the team struggles to save her and appease her very attentive husband, Ed (guest star Dominic Purcell). After Dr. House and Dr. Wilson treat a woman at the clinic with new breast implants, the idea that House's new patient Elyse may have breast cancer is raised as a possible diagnosis. But that diagnosis fails to be the answer when Elyse lapses into a coma after starting treatment. House starts to suspect Elyse has contracted a rare sexually transmitted disease, but when Ed and Elyse are questioned individually, they each deny having an affair. To save their patient's life, the team has to acknowledge that House is right: everybody lies in the "Fidelity" episode of HOUSE Tuesday, Dec. 28 (9:00-10:00 PM ET/PT) on FOX. (HOU-107) (TV-TBA)

Cast: Hugh Laurie as Dr. Gregory House; Lisa Edelstein as Dr. Lisa Cuddy; Omar Epps as Dr. Eric Foreman; Robert Sean Leonard as Dr. James Wilson; Jennifer Morrison as Dr. Allison Cameron; Jesse Spencer as Dr. Robert Chase.

Guest Cast: Dominic Purcell as Ed; Myndy Crist as Elyse; Brennan Elliott as Adam; Clementine Ford as Sam; Henri Lubatti as Jacques; Endre Hules as Sous Chef; James Conkle as Young Boy.