DR. HOUSE TAKES CUDDY'S CHALLENGE TO GO OFF HIS PAINKILLERS FOR A WEEK, BUT THE EFFECTS OF HIS WITHDRAWAL SYMPTOMS MAY PUT HIS PATIENT IN DANGER ON "HOUSE" TUESDAY, JUNE 28, ON FOX

While trying to figure out why a young patient won't stop bleeding, House takes Cuddy's challenge and goes off Vicodin for a week in exchange for no clinic duty for a month. If House and his team can't determine the source of his patient's blood loss, the 16-year-old car accident victim will die in a matter of days. As House's withdrawal symptoms become more and more severe, his directives for his patient are more harsh and risky than usual, leading Foreman and Cameron to fear he may not be thinking clearly enough to save the patient's life in the "Detox" episode of HOUSE Tuesday, June 28 (9:00-10:00 PM ET/PT) on FOX. (HOU-112) (TV-14 S, L, V)

Cast: Hugh Laurie as Dr. Gregory House; Lisa Edelstein as Dr. Lisa Cuddy; Omar Epps as Dr. Eric Foreman; Robert Sean Leonard as Dr. James Wilson; Jennifer Morrison as Dr. Allison Cameron; Jesse Spencer as Dr. Robert Chase.

Guest Cast: Mark Harelik as Mr. Foster; Nicholas D'Agosto as Keith; Amanda Seyfried as Pam; Marco Pelaez as Pharmacist; America Olivo as Ingrid; Maurice Godin as Dr. Hourani; Akiko Ann Morison as Anesthesiologist