TUESDAY, SEPTEMBER 16

**SEASON PREMIERE**�"HOUSE"�(8:00-9:00 PM ET/PT) CC-HDTV 720p-Dolby Digital 5.1

PA: Viewer discretion is advised.

IN THE AFTERMATH OF AMBER'S DEATH, WILSON ANNOUNCES HIS RESIGNATION ON THE SEASON PREMIERE OF "HOUSE" TUESDAY, SEPTEMBER 16, ON FOX

Eight weeks after the death of his girlfriend, Amber, Wilson is still mourning her death, and his relationship with his best friend House is shattered. Needing to make a change in his life and give himself time to recover emotionally, Wilson resigns from Princeton-Plainsboro. He is forced to decide if House is a destructive force in his life, while House has to determine if he's responsible for the death of his best friend's girlfriend. The team must push forward as they encounter a case involving an assistant to a high-profile executive, who is a textbook "Type A" personality. The team suspects that the patient's symptoms stem from her obsession to constantly please her demanding boss. However, her shocking medical condition forces the team to rethink their initial diagnoses and see the case through House's eyes. Meanwhile, Cuddy attempts to salvage the irreparable rift between House and Wilson, and Thirteen struggles to treat the patient objectively without bringing the reality of her own medical condition to the case in the "Dying Changes Everything" episode of HOUSE airing Tuesday, Sept. 16 (8:00-9:00 PM ET/ PT) on FOX. (HOU-501) (TV-14 D)

Cast: Hugh Laurie as Dr. Gregory House; Lisa Edelstein as Dr. Lisa Cuddy; Omar Epps as Dr. Eric Foreman; Robert Sean Leonard as Dr. James Wilson; Jennifer Morrison as Dr. Allison Cameron; Jesse Spencer as Dr. Robert Chase; Peter Jacobson as Dr. Chris Taub; Kal Penn as Dr. Lawrence Kutner; Olivia Wilde as Thirteen

Guest Cast: Christine Woods as Lou; Jamie Rose as Patty; David Kagen as C.E.O.; Paul Haitkin as Another Suit; Bob Sherer as Patient; Janet Song as Surgeon; Bobbin Bergstrom as Nurse.