FRIDAY, MAY 21

--"HOUSE"-(8:00-9:00 PM ET/PT) CC-HDTV 720p-Dolby Digital 5.1

PA: Viewer discretion is advised.

A PATIENT OPENS UP ON "HOUSE" FRIDAY, MAY 21, ON FOX

Sarah Wayne Callies ("Prison Break") and Cynthia Watros Guest-Star

House and the team take on the case of a woman Julia (guest star Callies), who is in an open marriage and becomes ill during a date with her on-the-side boyfriend. As perplexing as the case is, Julia's happy and healthy, yet polygamous relationship is equally baffling to the team. Meanwhile, House tests Wilson's relationship with Sam (guest star Watros) and Taub attempts a new level in his relationship with his wife Rachel in the "Open and Shut" episode of HOUSE airing Friday, May 21 (8:00-9:00 PM ET/PT) on FOX. (HOU-619) (TV-14 D, L, S)

Cast: Hugh Laurie as Dr. Gregory House; Lisa Edelstein as Dr. Lisa Cuddy; Omar Epps as Dr. Eric Foreman; Robert Sean Leonard as Dr. James Wilson; Jennifer Morrison as Dr. Allison Cameron; Jesse Spencer as Dr. Robert Chase; Peter Jacobson as Dr. Chris Taub; Olivia Wilde as Thirteen/ Dr. Remy Hadley

Guest Cast: Jennifer Crystal Foley as Rachel Taub; Cynthia Watros as Sam Carr; Sarah Wayne Callies as Julia; Rob Evors as Tom; Erica Teeple as Evelyn; Danna Brady as Maya; Charlie Weber as Damien; Liz Benoit as Nurse Anne