HOW DO YOU SOLVE A MURDER WITHOUT THE VICTIM'S BODY?, ON ABC'S "CASTLE"

"Head Case" - Gunshots, a fleeing van and a massive blood pool all point to murder, but when Castle & Beckett arrive at the crime scene, they discover that it lacks something - the victim! The investigation leads to the cutting-edge world of life-extension science, a cunning high-tech researcher (guest star William Atherton), and a sleazy porn mogul who invested in a modern-day "fountain of youth." Meanwhile, Alexis finds out whether she got into Stanford, on "Castle," MONDAY, OCTOBER 3 (10:01-11:00 p.m., ET), on the ABC Television Network.

"Castle" stars Nathan Fillion as Richard Castle, Stana Katic as NYPD Detective Kate Beckett, Susan Sullivan as Martha Rodgers, Molly Quinn as Alexis Castle, Penny Johnson Jerald as NYPD Captain Victoria Gates, Tamala Jones as Medical Examiner Lanie Parish, Jon Huertas as NYPD Detective Javier Esposito, and Seamus Dever as NYPD Detective Kevin Ryan.

Guest Cast: William Atherton as Dr. Ari Weiss, Andy Umberger as Johnny Rosen, Judith Hoag as Cynthia Hamilton, Shaun Toub as Dr. Philip Boyd, Jordan Belfi as Beau Randolph, Jared Hillman as Eddie Peck.

"Head Case" was written by David Grae and directed by Holly Dale.

"Castle" is broadcast in 720 Progressive (720P), ABC's selected HDTV format, with 5.1 channel surround sound. A TV parental guideline will be assigned closer to airdate.